Receptor Epitope Usage by an Interleukin-5 Mimetic Peptide
نویسندگان
چکیده
منابع مشابه
Receptor epitope usage by an interleukin-5 mimetic peptide.
The cyclic peptide AF17121 is a library-derived antagonist for human interleukin-5 (IL5) receptor alpha (IL5Ralpha) and inhibits IL5 activity. Our previous results have demonstrated that the sixth arginine residue of the peptide is crucial for the inhibitory effect and that several acidic residues in the N- and C-terminal regions also make a contribution, although to a lesser extent (Ruchala, P...
متن کاملReceptor Epitope Usage by Interleukin 5 Mimetic Peptide
Tetsuya Ishino, Cecilia Urbina, Madhushree Bhattacharya, Dominick Panarello, and Irwin Chaiken From the Department of Biochemistry and Molecular Biology, and A. J. Drexel Institute of Basic and Applied Protein Science, Drexel University College of Medicine, Philadelphia, PA, 19102 Running Title: Receptor Epitope Usage by Interleukin 5 Mimetic Peptide Address correspondence to: Irwin Chaiken, De...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2005
ISSN: 0021-9258
DOI: 10.1074/jbc.m502341200